All-in-one stability indicating polysorbate 20 degradation root-cause analytics via UPLC-QDa

Author:

Carle StefanORCID,Evers Dirk-H.,Hagelskamp Elina,Garidel Patrick,Buske Julia

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference67 articles.

1. Formulation of biologics including biopharmaceutical considerations;Crommelin,2019

2. Key interactions of surfactants in therapeutic protein formulations: A review;Khan;Eur. J. Pharm. Biopharm.,2015

3. Surface tension and self-association properties of aqueous polysorbate 20 HP and 80 HP solutions: insights into protein stabilisation mechanisms;Garidel;J. Pharm. Innov.,2020

4. Ehsan, M. Dehghan, N. Gholamreza, Effect of temperature on the critical micelle concentration and micellization thermodynamic of nonionic surfactants: polyoxyethylene sorbitan fatty acid esters. J Chem-ny 9, 2268–2274 (2012).

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