Development and validation of an LC-MS/MS method for the quantification of KRASG12C inhibitor opnurasib in several mouse matrices and its application in a pharmacokinetic mouse study-Reference-Cited by-同舟云学术

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Development and validation of an LC-MS/MS method for the quantification of KRASG12C inhibitor opnurasib in several mouse matrices and its application in a pharmacokinetic mouse study

Published:2024-01 Issue: Volume:1232 Page:123964
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Retmana Irene A.,Çelebi Nefise,Rijmers Jamie,Schinkel Alfred H.,Beijnen Jos H.,Sparidans Rolf W.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference22 articles.

1. Oncogenic signaling pathways in the cancer genome atlas;Sanchez-Vega;Cell,2018

2. Drugging the undruggable RAS: mission possible?;Cox;Nat. Rev. Drug Discov.,2014

3. Characteristics and outcomes of patients with metastatic KRAS-mutant lung adenocarcinomas: The Lung Cancer Mutation Consortium Experience;El Osta;J. Thorac. Oncol.,2019

4. Clinical characteristics and prognostic value of the KRAS G12C mutation in Chinese non-small cell lung cancer patients;Liu;Biomark. Res.,2020

5. J.M. Ostrem, U. Peters, M.L. Sos, et al., K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions, Nat. 503 (2013) 548–551, doi: 10.1038/NATURE12796.

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure;Biomedicine & Pharmacotherapy;2024-06

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