Development and validation of LC–MS/MS assays for the quantification of E7080 and metabolites in various human biological matrices-Reference-Cited by-同舟云学术

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Development and validation of LC–MS/MS assays for the quantification of E7080 and metabolites in various human biological matrices

Published:2012-03 Issue: Volume:887-888 Page:25-34
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Dubbelman A.C.,Rosing H.,Thijssen B.,Gebretensae A.,Lucas L.,Chen H.,Shumaker R.,Schellens J.H.M.,Beijnen J.H.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference11 articles.

1. E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

2. E7080, a Multi-Tyrosine Kinase Inhibitor, Suppresses the Progression of Malignant Pleural Mesothelioma with Different Proangiogenic Cytokine Production Profiles

3. Multi-Kinase Inhibitor E7080 Suppresses Lymph Node and Lung Metastases of Human Mammary Breast Tumor MDA-MB-231 via Inhibition of Vascular Endothelial Growth Factor-Receptor (VEGF-R) 2 and VEGF-R3 Kinase

4. A phase I study of E7080 in patients (pts) with advanced malignancies;Glen;J. Clin. Oncol.,2008

5. A phase II trial of the multitargeted kinase inhibitor E7080 in advanced radioiodine (RAI)-refractory differentiated thyroid cancer (DTC);Sherman;J. Clin Oncol.,2011

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