Characterization and identification of alanine to serine sequence variants in an IgG4 monoclonal antibody produced in mammalian cell lines-Reference-Cited by-同舟云学术

Characterization and identification of alanine to serine sequence variants in an IgG4 monoclonal antibody produced in mammalian cell lines

Published:2012-11 Issue: Volume:908 Page:1-8
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Fu Jinmei,Bongers Jacob,Tao Li,Huang Dan,Ludwig Richard,Huang Yunping,Qian Yueming,Basch Jonathan,Goldstein Joel,Krishnan Ramji,You Li,Li Zheng Jian,Russell Reb J.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference37 articles.

1. Variant antibody identification by peptide mapping

2. Assessing Genetic Heterogeneity in Production Cell Lines: Detection by Peptide Mapping of a Low Level Tyr to Gln Sequence Variant in a Recombinant Antibody

3. Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells

4. Identification of Codon-Specific Serine to Asparagine Mistranslation in Recombinant Monoclonal Antibodies by High-Resolution Mass Spectrometry

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