A rapid and sensitive liquid chromatography/tandem mass spectrometry assay for simultaneous quantitation of disopyramide and its major metabolite, mono-isopropyl-disopyramide, in rat plasma and its application to a pharmacokinetic study
Author:
Funder
Ministry of Education
Publisher
Elsevier BV
Subject
Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry
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1. Antiarrhythmic agents and their use in therapy
2. Effects of intravenous disopyramide and quinidine on normal myocardium and on the characteristics of arrhythmias: intraindividual comparison in patients with sustained ventricular tachycardia
3. Disopyramide serum and pharmacologic effect kinetics applied to the assessment of bioavailability.
4. Clinical pharmacokinetics of disopyramide
5. Plasma binding of disopyramide and mono-N-dealkyldisopyramide.
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