Comprehensive characterization of in vitro and in vivo metabolites of 2′,3′,5′‑tri‑O‑acetyl‑N6‑(3‑hydroxyphenyl) adenosine and study of the metabolites distribution in rats by combined methods of HPLC-DAD, off-line cryoNMR, and HPLC-QTOFMS-Reference-Cited by-同舟云学术

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Comprehensive characterization of in vitro and in vivo metabolites of 2′,3′,5′‑tri‑O‑acetyl‑N6‑(3‑hydroxyphenyl) adenosine and study of the metabolites distribution in rats by combined methods of HPLC-DAD, off-line cryoNMR, and HPLC-QTOFMS

Published:2018-10 Issue: Volume:1096 Page:187-200
ISSN:1570-0232
Container-title:Journal of Chromatography B
language:en
Short-container-title:Journal of Chromatography B

Author:

Jin Mengxia,Guo Na,Li Tianqi,Liu Xia,Sun Shanshan,Jin Xiangju,Zhu Haibo,Qin Hailin,Wang Yinghong

Funder

National High Technology Research and Development Program of China

National S&T Major Project

Innovation Fund for Medical Sciences

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference37 articles.

1. Cordycepin: a bioactive metabolite with therapeutic potential;Tuli;Life Sci.,2013

2. A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells;Lian;Lipids Health Dis.,2011

3. The adenosine derivative 2′,3′,5′‑tri‑O‑acetyl‑N6‑(3‑hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo;Guo;Life Sci.,2012

4. AMP-activated protein kinase attenuates oxLDL uptake in macrophages through PP2A/NF-kappaB/LOX-1 pathway;Chen;Vasc. Pharmacol.,2016

5. AMPK activation enhances the anti-atherogenic effects of high density lipoproteins in apoE−/− mice;Ma;J. Lipid Res.,2017

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 2′, 3′, 5′-tri-O-acetyl-N6-(3-hydroxyphenyl) adenosine alleviates diet-induced hyperlipidemia by modulating intestinal gene expression profiles and metabolic pathway;Life Sciences;2024-09

2. Discovery of novel (6S/12aS)-heptachpyridone capable of inhibiting thrombosis in vivo;Bioorganic & Medicinal Chemistry Letters;2020-10

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