Optimizing host cell physiology and stress avoidance for the production of recombinant human tumour necrosis factor α in Escherichia coli-Reference-Cited by-同舟云学术

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Optimizing host cell physiology and stress avoidance for the production of recombinant human tumour necrosis factor α in Escherichia coli

Published:2018-04-01 Issue:4 Volume:164 Page:440-452
ISSN:1350-0872
Container-title:Microbiology
language:en
Short-container-title:

Author:

Selas Castiñeiras Tania¹²³,Williams Steven G.¹,Hitchcock Antony¹,Cole Jeffrey A.³⁴,Smith Daniel C.¹,Overton Tim W.³²

Affiliation:

1. Cobra Biologics, Stephenson Building, The Science Park, Keele ST5 5SP, UK

2. School of Chemical Engineering, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

3. Institute of Microbiology & Infection, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

4. School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Publisher

Microbiology Society

Subject

Microbiology

Reference18 articles.

1. Microbials for the production of monoclonal antibodies and antibody fragments

2. Recombinant protein production in bacterial hosts

3. Solubilization and refolding of bacterial inclusion body proteins

4. Periplasmic expression in and release of Fab fragments fromEscherichia coliusing stress minimization

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Optimisation of recombinant TNFα production in Escherichia coli using GFP fusions and flow cytometry;Frontiers in Bioengineering and Biotechnology;2023-08-02

2. A De Novo Optimized Cell-Free System for the Expression of Soluble and Active Human Tumor Necrosis Factor-Alpha;Biology;2022-01-19

3. Active Human and Murine Tumor Necrosis Factor α Cytokines Produced from Silkworm Baculovirus Expression System;Insects;2021-06-02

4. Kinetic study and optimization of recombinant human tumor necrosis factor-alpha (rhTNF-α) production in Escherichia coli;Preparative Biochemistry & Biotechnology;2020-09-02

5. Use of a design of experiments approach to optimise production of a recombinant antibody fragment in the periplasm of Escherichia coli: selection of signal peptide and optimal growth conditions;AMB Express;2019-01-07

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