Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces

Author:

Lemmer Karin1,Mielke Martin2,Kratzel Christine1,Joncic Marion1,Oezel Muhsin3,Pauli Georg4,Beekes Michael1

Affiliation:

1. P24, Transmissible Spongiform Encephalopathies, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany

2. FG 14, Applied Infection Control and Hospital Hygiene, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany

3. ZBS4, Centre for Biological Safety – Imaging Techniques for Rapid Morphology-Based Diagnostics of Infectious Organisms, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany

4. ZBS1, Centre for Biological Safety – Highly Pathogenic Viruses, Robert Koch-Institut, Nordufer 20, 13353 Berlin, Germany

Publisher

Microbiology Society

Subject

Virology

Reference27 articles.

1. Activity of an alkaline cleaner in the inactivation of the scrapie agent;Baier;J Hosp Infect,2004

2. Elimination of transmissible spongiform encephalopathy infectivity and decontamination of surgical instruments by using radio-frequency gas-plasma treatment;Baxter;J Gen Virol,2005

3. Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie;Beekes;J Gen Virol,1996

4. Aspects of risk assessment and risk management of nosocomial transmission of classical and variant Creutzfeldt–Jakob disease with special attention to German regulations;Beekes,2004

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