Multiple recombinant dengue type 1 viruses in an isolate from a dengue patient-Reference-Cited by-同舟云学术

Multiple recombinant dengue type 1 viruses in an isolate from a dengue patient

Published:2007-12-01 Issue:12 Volume:88 Page:3334-3340
ISSN:0022-1317
Container-title:Journal of General Virology
language:en
Short-container-title:

Author:

Aaskov John¹,Buzacott Katie¹,Field Emma¹,Lowry Kym¹,Berlioz-Arthaud Alain²,Holmes Edward C.³⁴

Affiliation:

1. Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia

2. Institute Pasteur, Noumea, New Caledonia

3. Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA

4. Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, Mueller Laboratory, University Park, PA 16802, USA

Abstract

Between 2000 and 2004, dengue virus type 1 (DENV-1) genotypes I and II from Asia were introduced into the Pacific region and co-circulated in some localities. Envelope protein gene sequences of DENV-1 from 12 patients infected on the island of New Caledonia were obtained, five of which carried genotype I viruses and six, genotype II viruses. One patient harboured a mixed infection, containing viruses assigned to both genotypes I and II, as well as a number of inter-genotypic recombinants. This is the first report of a population of dengue viruses isolated from a patient containing both parental and recombinant viruses.

Publisher

Microbiology Society

Subject

Virology

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