Production of a non-toxic site-directed mutant of Clostridium perfringens ε-toxin which induces protective immunity in mice
Author:
Affiliation:
1. Defence Evaluation and Research Agency, CBD Porton Down, Salisbury, Wiltshire SP4 0JQ, UK
Abstract
Publisher
Microbiology Society
Subject
Microbiology
Reference34 articles.
1. Structural studies on ε- prototoxin of Clostridium perfingens type D. Localisation of the site of tryptic scission necessary for activation to ε-toxin.;Bhown;Biochem Biophys Res Commun,1977
2. Suggestions for ‘safe’ residue substitutions in site-directed mutagenesis.;Bordo;J Mol Biol,1991
3. A reassessment of the criteria used for type differentiation of Clostridium perfringens;Brooks;J Pathol Bacteriol,1957
4. The effect of Clostridium welcbii type D culture filtrates on the permeability of the mouse intestine.;Bullen;J Pathol Bacteriol,1956
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