IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex-Reference-Cited by-同舟云学术

IS990, a new species-specific insertion-sequence-related element of the Mycobacterium tuberculosis complex

Published:1998-12-01 Issue:12 Volume:144 Page:3407-3412
ISSN:1350-0872
Container-title:Microbiology
language:en
Short-container-title:

Author:

Dziadek J.¹,Sajduda A.²,Dale J. W.³,McFadden J. J.³

Affiliation:

1. Centre for Microbiology and Virology, Polish Academy of Sciences, Lodowa 106, 93-232 Ldz, Poland

2. Department of Genetics of Microorganisms, University of Ldz, Banacha 12/16, 93237 Ldz, Poland

3. Molecular Microbiology Group, School of Biological Sciences, University of Surrey, Guildford GU2 5XH, UK

Abstract

Summary: The structure and distribution of IS990, a new Mycobacterium tuberculosis DNA sequence with homology to characterized insertion sequences (ISs), were investigated. IS990 was related to IS elements of the IS3 family and was present as a single copy in all 21 investigated M. tuberculosis strains, two Mycobacterium bovis strains and two M. bovis BCG strains. The sequence appears to be specific for the M. tuberculosis complex. The element carries two frameshift mutations and appears to be defective.

Publisher

Microbiology Society

Subject

Microbiology

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