Affiliation:
1. Department of Microbiology, University of Pennsylvania School of Medicine,Philadelphia, PA 19104-6076,USA
Abstract
A mutation, bofC1, that restores σK activation in Bacillus subtilis strains unable to produce active σG has been identified. This mutation defines a new sporulation gene, bofC, that has been cloned and sequenced and encodes a 19 kDa protein. bofC is transcribed in the forespore by RNA polymerase associated with the transcription factors σF (EσF) and σG (EσG). BofC acts negatively on SpolVB and the results described suggest that BofC regulates SpolVB activity and its intercompartmental signalling role in the σK checkpoint
Cited by
23 articles.
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