Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity a aDetails for the preparation of the thiolactomycin analogues shown in Table 1 are available as supplementary data in Microbiology Online (http://mic.sgmjournals.org).-Reference-Cited by-同舟云学术

Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity a aDetails for the preparation of the thiolactomycin analogues shown in Table 1 are available as supplementary data in Microbiology Online (http://mic.sgmjournals.org).

Published:2002-10-01 Issue:10 Volume:148 Page:3101-3109
ISSN:1350-0872
Container-title:Microbiology
language:en
Short-container-title:

Author:

Douglas James D.¹,Senior Suzanne J.²³¹,Morehouse Caroline⁴,Phetsukiri Benjawan⁴,Campbell Ian B.²,Besra Gurdyal S.³,Minnikin David E.³

Affiliation:

1. Department of Chemistry, University of Newcastle, Newcastle-upon-Tyne NE1 7RU, UK1

2. GlaxoSmithKline Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK3

3. School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK2

4. Department of Microbiology, Colorado State University, Fort Collins, CO 80523-1677, USA4

Publisher

Microbiology Society

Subject

Microbiology

Reference24 articles.

1. Asymmetric synthesis of 5,5-disubstituted thiotetronic acids using an allyl xanthate to dithiocarbonate rearrangement: total synthesis of (5 S) -thiolactomycin with revision of the absolute configuration of the natural product;Chambers;J Chem Soc Perkin Trans I,1997

2. Identification and substrate specificity of beta-ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis;Choi;J Biol Chem,2000

3. Antimicrobial activities of thiolactomycin against gram-negative anaerobes associated with periodontal disease;Hamada;Oral Microbiol Immunol,1990

4. Mechanism of action of the antibiotic thiolactomycin inhibition of fatty acid synthesis of Escherichia coli;Hayashi;Biochem Biophys Res Commun,1983

5. Inhibition of fatty acid synthesis by the antibiotic thiolactomycin;Hayashi;J Antibiot,1984

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