Pseudomonas aeruginosa mutations in lasI and rhlI quorum sensing systems result in milder chronic lung infection

Author:

Wu Hong1,Song Zhijun21,Givskov Michael3,Doring Gerd4,Worlitzsch Dieter4,Mathee Kalai2,Rygaard Jørgen5,Høiby Niels1

Affiliation:

1. Department of Clinical Microbiology, 9301 Rigshospitalet, Juliane Maries Vej 22, DK-2100, Copenhagen Ø, Denmark1

2. Department of Biological Sciences, Florida International University, University Park, Miami, FL 33199, USA4

3. Institute of Microbiology, Technical University of Denmark, DK-2800, Lyngby, Denmark2

4. Hygiene Institute, University of Tübingen,D-72074, Tübingen, Germany3

5. Bartholin Institute, Kommunehospitalet, Copenhagen, Denmark5

Publisher

Microbiology Society

Subject

Microbiology

Reference64 articles.

1. Role of mast cells in bacterial clearance in the lung;Abraham;Mucosal Immunology Update,1996

2. Functional importance of cystic fibrosis immunoglobulin G fragments generated by Pseudomonas aeruginosa elastase;Bainbridge;J Lab Clin Med,1989

3. Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family;Brint;J Bacteriol,1995

4. Regulation of the xcp secretion pathway by multiple quorum-sensing modulons in Pseudomonas aeruginosa;Chapon-Herve;Mol Microbiol,1997

5. Development of antibiotic resistance in Pseudomonas aeruginosa during two decades of antipseudomonal treatment at the Danish CF Center;Ciofu;APMIS,1994

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