Draft genome sequence of Enterobacter cloacae ST473 harbouring blaCMH-3 isolated from a human patient diagnosed with recurrent bacteriuria in Nigeria-Reference-Cited by-同舟云学术

Draft genome sequence of Enterobacter cloacae ST473 harbouring blaCMH-3 isolated from a human patient diagnosed with recurrent bacteriuria in Nigeria

Published:2023-07-01 Issue:7 Volume:5 Page:
ISSN:2516-8290
Container-title:Access Microbiology
language:en
Short-container-title:

Author:

David Ebuka Elijah¹²^ORCID,Igwenyi Ikechuku Okorie³^ORCID,Iroha Ifeanyichukwu Romanus⁴^ORCID,Martins Layla Farage¹,Uceda-Campos Guillermo¹^ORCID,da Silva Aline Maria¹^ORCID

Affiliation:

1. Department of Biochemistry, Institute of Chemistry, University of Sao Paulo, Sao Paulo, Brazil

2. Department of Biochemistry, Alex Ekwueme Federal University, Ndufu-Alike, Ikwo, Nigeria

3. Department of Biochemistry, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria

4. Department of Microbiology, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria

Abstract

Enterobacter cloacae

is among the most frequently isolated species described in clinical infections and is commonly associated with a multidrug resistance (MDR) phenotype. We present the draft genome sequence of a MDR

E. cloacae

isolated in Nigeria from the urine sample of an adult male outpatient diagnosed with symptomatic recurrent bacteriuria. The isolate was found to be resistant to ceftriaxone, cefotaxime, cefepime and levofloxacin. Genome analysis revealed the presence of the beta-lactamase chromosomal gene blaCMH-3, which may be responsible for the antibiotic resistance observed in the recurrent

E. cloacae

urinary tract infection.

Funder

International Center for Genetic Engineering and Biotechnology

Publisher

Microbiology Society

Subject

Microbiology (medical),Microbiology

Link

https://www.microbiologyresearch.org/content/journal/acmi/10.1099/acmi.0.000565.v3?crawler=true&mimetype=application/pdf

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