Mortality difference from Klebsiella aerogenes vs Enterobacter cloacae bloodstream infections-Reference-Cited by-同舟云学术

Mortality difference from Klebsiella aerogenes vs Enterobacter cloacae bloodstream infections

Published:2023-02-27 Issue:2 Volume:5 Page:
ISSN:2516-8290
Container-title:Access Microbiology
language:en
Short-container-title:

Author:

Chou Andrew¹²³⁴^ORCID,Sucgang Richard⁵⁴,Hamill Richard J.²⁴¹,Zechiedrich Lynn⁶⁷⁴,Trautner Barbara W.⁸⁴³

Affiliation:

1. Medical Care Line, Infectious Disease Section, Michael E. DeBakey VA Medical Center, Houston, Texas, 2002 Holcombe Blvd 111G/4B370, Houston, Texas, USA

2. Margaret M. and Albert B. Alkek Department of Medicine Section of Infectious Disease, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA

3. Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey VA Medical Center, 2450 Holcombe Blvd, Suite 01Y, Houston, Texas, USA

4. Department of Molecular Virology and Microbiology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA

5. Center for Health Data Science and Analytics, Houston Methodist Hospital, 6565 Fannin St, Houston, Texas, USA

6. Department of Pharmacology and Chemical Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA

7. Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA

8. Section of Health Services Research, Departments of Medicine and Surgery, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA

Abstract

Members of the order Enterobacterales, including

Escherichia coli

Klebsiella

species and

Enterobacter

species, are important pathogens in healthcare-associated infections. Higher mortality has been reported from infections due to

Klebsiella pneumoniae

than from

E. coli

, but prior studies comparing

Enterobacter aerogenes

(recently renamed

Klebsiella aerogenes

) bacteraemia and

Enterobacter cloacae

complex bacteraemia have yielded conflicting results regarding whether clinical outcomes differ. We found bacteraemia with

K. aerogenes

was independently associated with greater risk of 30-day mortality than bacteraemia with

Enterobacter cloacae

complex.

Funder

U.S. Department of Veterans Affairs

National Institute of Allergy and Infectious Diseases

National Institute of General Medical Sciences

Publisher

Microbiology Society

Subject

General Medicine

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