Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo-Reference-Cited by-同舟云学术

Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo

Published:2018-10-01 Issue:10 Volume:99 Page:1381-1390
ISSN:0022-1317
Container-title:Journal of General Virology
language:en
Short-container-title:

Author:

Laconi Andrea¹,van Beurden Steven J.¹²,Berends Alinda J.¹,Krämer-Kühl Annika³,Jansen Christine A.⁴,Spekreijse Dieuwertje⁵⁶,Chénard Gilles⁵⁷,Philipp Hans-Christian³,Mundt Egbert³,Rottier Peter J. M.⁸,Hélène Verheije M.¹

Affiliation:

1. 1Faculty of Veterinary Medicine, Department Pathobiology, Pathology Division, Utrecht University, Utrecht, 3584CL, The Netherlands

2. †Present address: Gupta Strategists, Ophemert, The Netherlands.

3. 2Boehringer Ingelheim Veterinary Research Center GmbH & Co. KG, Hannover, Germany

4. 3Faculty of Veterinary Medicine, Department Infectious Diseases and Immunology, Immunology Division, Utrecht University, Utrecht, 3584CL, The Netherlands

5. 4Boehringer Ingelheim Animal Health Operations BV, Weesp, The Netherlands

6. ‡Present address: Intravacc Animal Research Centre, Ponwalla Science Park, The Netherlands.

7. §Present address: Thermo Fisher Scientific, 8211AR Lelystad, The Netherlands.

8. 5Faculty of Veterinary Medicine, Department Infectious Diseases and Immunology, Virology Division, Utrecht University, Utrecht, 3584CL, The Netherlands

Publisher

Microbiology Society

Subject

Virology

Reference26 articles.

1. Infectious bronchitis;Jackwood,2013

2. Manipulation of the infectious bronchitis coronavirus genome for vaccine development and analysis of the accessory proteins

3. Accessory proteins of SARS-CoV and other coronaviruses

4. Gene 5 of the Avian Coronavirus Infectious Bronchitis Virus Is Not Essential for Replication

5. The Group-Specific Murine Coronavirus Genes Are Not Essential, but Their Deletion, by Reverse Genetics, Is Attenuating in the Natural Host

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