Generation of a potential koi herpesvirus live vaccine by simultaneous deletion of the viral thymidine kinase and dUTPase genes

Author:

Schröder Lars1,Klafack Sandro2,Bergmann Sven M.2,Fichtner Dieter2,Jin Yeonhwa2,Lee Pei-Yu3,Höper Dirk4,Mettenleiter Thomas C.1,Fuchs Walter1

Affiliation:

1. 1​Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

2. 2​Institute of Infectology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

3. 3​GeneReach Biotechnology Corporation, Taichung, Taiwan, ROC

4. 4​Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

Publisher

Microbiology Society

Subject

Virology

Reference43 articles.

1. Mass mortalities in koi, Cyprinus carpio, associated with gill and skin disease;Bretzinger;Bull Eur Ass Fish Pathol,1999

2. A herpesvirus associated with mass mortality of juvenile and adult koi, a strain of a common carp;Hedrick;Fish Health Newsletter,1999

3. Isolation of a virus from koi with altered gills;Neukirch;Bull Eur Assoc Fish Pathol,1999

4. Efficient vaccine against the virus causing a lethal disease in cultured Cyprinus carpio

5. CyHV-3: the third cyprinid herpesvirus

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