A novel B/C inter-genotype recombinant of hepatitis B virus identified in north-west China

Author:

Chen Xiaoming1,Dai Bangyao2,Liu Zhengcai2,Gao Jie1,Ji Zhaohua1,Guo Jutao3,Chen Gang4,Deng Zhongrong1,Shao Zhongjun1

Affiliation:

1. Department of Epidemiology, Fourth Military Medical University, 169 Changle West Road, Xi’an 710032, PR China

2. Department of Hepatobiliary Surgery, Xijing Hospital, 169 Changle West Road, Xi’an 710032, PR China

3. Department of Microbiology and Immunology, Drexel University College of Medicine, 2900 W. Queen Lane, Philadelphia, PA 19129, USA

4. Hepatitis B Foundation, 3805 Old Easton Road, Doylestown, PA 18902, USA

Abstract

The characteristics of life-long persistent infection of hepatitis B virus (HBV) and the prevalence of different genotypes of HBV in China may cause new recombinants. In north-west China, HBV inter-genotype recombinants have been reported frequently over the last decade. Here, we report a B/C inter-genotype recombinant HBV with a novel genome mosaic structure from Lanzhou, a city in north-west China.

Publisher

Microbiology Society

Subject

Virology

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