Kolente virus, a rhabdovirus species isolated from ticks and bats in the Republic of Guinea

Author:

Ghedin Elodie1,Rogers Matthew B.1,Widen Steven G.2,Guzman Hilda3,Travassos da Rosa Amelia P. A.3,Wood Thomas G.2,Fitch Adam1,Popov Vsevolod453,Holmes Edward C.67,Walker Peter J.8,Vasilakis Nikos453,Tesh Robert B.453

Affiliation:

1. Center for Vaccine Research, Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

2. Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA

3. Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA

4. Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA

5. Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX, USA

6. Fogarty International Center, National Institutes of Health, Bethesda, MD, USA

7. Sydney Emerging Infections & Biosecurity Institute, School of Biological Sciences and Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia

8. CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong, VIC 3220, Australia

Abstract

Kolente virus (KOLEV) is a rhabdovirus originally isolated from ticks and a bat in Guinea, West Africa, in 1985. Although tests at the time of isolation suggested that KOLEV is a novel rhabdovirus, it has remained largely uncharacterized. We assembled the complete genome sequence of the prototype strain DakAr K7292, which was found to encode the five canonical rhabdovirus structural proteins (N, P, M, G and L) with alternative ORFs (>180 nt) in the P and L genes. Serologically, KOLEV exhibited a weak antigenic relationship with Barur and Fukuoka viruses in the Kern Canyon group. Phylogenetic analysis revealed that KOLEV represents a distinct and divergent lineage that shows no clear relationship to any rhabdovirus except Oita virus, although with limited phylogenetic resolution. In summary, KOLEV represents a novel species in the family Rhabdoviridae.

Publisher

Microbiology Society

Subject

Virology

Reference41 articles.

1. Characterization of Durham virus, a novel rhabdovirus that encodes both a C and SH protein

2. Arboviruses;Beaty,1989

3. [Isolation of Rift Valley fever virus from bats in the Republic of Guinea];Boiro;Bull Soc Pathol Exot,1987

4. Phylogenetic relationships among rhabdoviruses inferred using the L polymerase gene

5. [Arbovirus circulation in the Republic of Guinea];Butenko;Med Parazitol (Mosk),1996

Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3