Genomic dissection of the Vibrio cholerae O-serogroup global reference strains: reassessing our view of diversity and plasticity between two chromosomes-Reference-Cited by-同舟云学术

Genomic dissection of the Vibrio cholerae O-serogroup global reference strains: reassessing our view of diversity and plasticity between two chromosomes

Published:2022-08-05 Issue:8 Volume:8 Page:
ISSN:2057-5858
Container-title:Microbial Genomics
language:en
Short-container-title:

Author:

Murase Kazunori¹²,Arakawa Eiji³,Izumiya Hidemasa³,Iguchi Atsushi⁴,Takemura Taichiro⁵,Kikuchi Taisei⁶¹,Nakagawa Ichiro²,Thomson Nicholas R.⁷⁸,Ohnishi Makoto³,Morita Masatomo³^ORCID

Affiliation:

1. Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

2. Department of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

3. Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan

4. Department of Animal and Grassland Sciences, Faculty of Agriculture, University of Miyazaki, Japan

5. Vietnam Research Station, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

6. Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan

7. London School of Hygiene and Tropical Medicine, London, UK

8. Wellcome Trust Sanger Institute, Hinxton, UK

Abstract

Approximately 200 O-serogroups of

Vibrio cholerae

have already been identified; however, only 2 serogroups, O1 and O139, are strongly related to pandemic cholera. The study of non-O1 and non-O139 strains has hitherto been limited. Nevertheless, there are other clinically and epidemiologically important serogroups causing outbreaks with cholera-like disease. Here, we report a comprehensive genome analysis of the whole set of

V. cholerae

O-serogroup reference strains to provide an overview of this important bacterial pathogen. It revealed structural diversity of the O-antigen biosynthesis gene clusters located at specific loci on chromosome 1 and 16 pairs of strains with almost identical O-antigen biosynthetic gene clusters but differing in serological patterns. This might be due to the presence of O-antigen biosynthesis-related genes at secondary loci on chromosome 2.

Publisher

Microbiology Society

Subject

General Medicine

Reference33 articles.

1. The Antigens of the Cholera Group of Vibrios

2. The Cholera Pandemic, Still with Us after Half a Century: Time to Rethink

3. Outbreak of gastro-enteritis by non agglutinable (NAG) vibrios = épidémie de gastro-entérite due a des vibrions non agglutinables;Weekly Epidemiological Record,1969

4. Severe Diarrhea Caused by Cholera Toxin–ProducingVibrio choleraeSerogroup O75 Infections Acquired in the Southeastern United States

5. Chitin Induces Natural Competence in Vibrio cholerae

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Vibrio cholerae serogroup O5 was responsible for the outbreak of gastroenteritis in Czechoslovakia in 1965;Microbial Genomics;2024-09-05

2. Interactions between pili affect the outcome of bacterial competition driven by the type VI secretion system;Current Biology;2024-06

3. Genomic epidemiology reveals multidrug resistant plasmid spread between Vibrio cholerae lineages in Yemen;Nature Microbiology;2023-09-28

4. Microbiome ownership for Indigenous peoples;Nature Microbiology;2023-09-28

5. Genomic insights into the 2022–2023Vibrio choleraeoutbreak in Malawi;2023-06-12