Development of imipenem resistance in an Aeromonas veronii biovar sobria clinical isolate recovered from a patient with cholangitis

Author:

Sánchez-Céspedes Javier1,Figueras Maria José2,Aspiroz Carmen3,Aldea Maria José3,Toledo Miguel3,Alperí Anabel2,Marco Francesc1,Vila Jordi1

Affiliation:

1. Servei de Microbiologia, Centre de Diagnòstic Biomèdic, Hospital Clínic, IDIBAPS, Facultat de Medicina, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain

2. Unitat de Microbiologia, Departament de Ciències Mèdiques Bàsiques, Facultat de Medicina i Ciències de la Salut, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Spain

3. Unidad de Microbiología, Hospital Royo Villanova, Avda San Gregorio 30, 59915 Zaragoza, Spain

Abstract

Several imipenem-susceptible and -resistantAeromonas veroniibiovar sobria isolates with different morphologies and antimicrobial susceptibilities recovered from bile samples of a patient with cholangitis were analysed. These isolates belonged to the same clone and the imipenem-resistant strains showed overexpression of theimiSgene, encoding a chromosomal carbapenemase. These results should make clinicians aware of the possible emergence of multidrug-resistantA. veroniibiovar sobria, perhaps as a consequence of previous treatment of a urinary tract infection with amoxicillin plus clavulanic acid.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

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