1. Infection and Immunity Section, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ, UK 2Department of Palliative Medicine, Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PT, UK 3Department of Oral Microbiology, GKT Dental Institute, Floor 28, Guy's Tower, Guy's Hospital, London SE1 9RT, UK