JMM Profile: Fosfomycin: a potential antibiotic for multi- and extensively resistant bacteria-Reference-Cited by-同舟云学术

JMM Profile: Fosfomycin: a potential antibiotic for multi- and extensively resistant bacteria

Published:2022-08-11 Issue:8 Volume:71 Page:
ISSN:0022-2615
Container-title:Journal of Medical Microbiology
language:en
Short-container-title:

Author:

Wangchinda Walaiporn¹^ORCID,Rattanaumpawan Pinyo¹^ORCID

Affiliation:

1. Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, Bangkoknoi, Bangkok 10700, Thailand

Abstract

Fosfomycin (FOF) is the first antimicrobial of the epoxide class. It is commercially available in oral and parenteral formulations. Oral FOF is widely used to treat uncomplicated cystitis in women, while parenteral FOF is extensively utilized for upper urinary tract infections. FOF has a broad-spectrum bactericidal activity with a low risk of cross-resistance to other antimicrobial classes. Therefore, parenteral FOF is increasingly prescribed adjunctive therapy to treat extra-urinary tract infections caused by multidrug-resistant, Gram-negative bacteria.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

Reference42 articles.

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