Mediterranean spotted fever with encephalitis

Author:

Aliaga Luis1,Sánchez-Blázquez Patricia1,Rodríguez-Granger Javier2,Sampedro Antonio2,Orozco Miguel1,Pastor Jorge3

Affiliation:

1. Faculty of Medicine (University of Granada), Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain

2. Service of Microbiology, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain

3. Service of Radiology, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, s/n, 18014 Granada, Spain

Abstract

Rickettsia conorii infection is endemic in the Mediterranean basin, where it is known as Mediterranean spotted fever, also known as Boutonneuse fever and Marseilles fever. We report the case of a 66-year-old diabetic man who presented a severe form of the disease, complicated by acute renal failure, thrombocytopenia and encephalitis. Diagnosis was confirmed by indirect immunofluorescence assay. Despite appropriate treatment, severe neurological sequelae have remained. Medical literature on encephalitis caused by R. conorii is also reviewed.

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

Reference16 articles.

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3. Fièvre Boutonneuse méditerranéenne révélée par une atteinte neurologique grave;Benhammou;Arch Fr Pediatr,1991

4. Guidelines for the diagnosis of tick-borne bacterial diseases in Europe;Brouqui;Clin Microbiol Infect,2004

5. Minocycline versus doxyxycline in the treatment of Lyme neuroborreliosis;Cunha;Clin Infect Dis,2000

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