Unveiling the complexity of rifampicin drug susceptibility testing in Mycobacterium tuberculosis: comparative analysis with next-generation sequencing

Author:

Qadir Mehmood12,Khan Muhammad Tahir345ORCID,Khan Sajjad Ahmed2,Akram Muhammad6,Canseco Julio Ortiz7,Faryal Rani1,Wei Dong Qing8910ORCID,Tahseen Sabira2

Affiliation:

1. Department of Microbiology, Quaid-i-Azam University, Islamabad 44000, Pakistan

2. National TB Control Program, National TB Reference Laboratory, Islamabad 44000, Pakistan

3. Zhongjing Research and Industrialization Institute of Chinese Medicine, Zhongguancun Scientific Park, Meixi, Nanyang, Henan 473006, PR China

4. Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore 58810, Pakistan

5. Department of Clinical Laboratory, State Key Laboratory of Respiratory Disease, Guangzhou Key Laboratory of Tuberculosis Research, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangzhou, PR China

6. Department of Life Sciences, School of Science, University of Management and Technology, Lahore, Pakistan

7. Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, London, UK

8. Zhongjing Research and Industrialization Institute of Chinese Medicine, Zhongguancun Scientific Park, Meixi, Nanyang, Henan, 473006, PR China

9. School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200030, PR China

10. Peng Cheng Laboratory, Vanke Cloud City Phase I Building 8, Xili Street, Nanshan District, Shenzhen, Guangdong, 518055, PR China

Abstract

Graphical abstract

Publisher

Microbiology Society

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