JMM Profile: Staphylococcus epidermidis

Author:

Skovdal Sandra Maria12ORCID,Jørgensen Nis Pedersen3ORCID,Meyer Rikke Louise45ORCID

Affiliation:

1. Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark

2. Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark

3. Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark

4. Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University, Aarhus, Denmark

5. Department of Biology, Faculty of Natural Sciences, Aarhus University, Aarhus, Denmark

Abstract

Staphylococcus epidermidis is the most abundant commensal bacterium of human skin. Despite protecting us from foreign invaders, S. epidermidis itself exploits human vulnerability when given the opportunity. Such opportunities arise when patients are immunocompromised or when biomedical implants present an opportunity to colonize the surface and form biofilms. S. epidermidis is one of the most frequently isolated organisms from implanted devices and from bloodstream infections. However, S. epidermidis infections are often recalcitrant to antibiotics because of biofilm-associated antibiotic tolerance. Furthermore, the emergence and spread of nearly pan-resistant strains is a considerable health concern. Symptoms can be subclinical, making diagnosis challenging, and treatment with antibiotics is inefficient. For now, infection prevention remains the best strategy available.

Funder

Carlsbergfondet

Sundhedsvidenskabelige Fakultet, Aarhus Universitet

Villum Fonden

Publisher

Microbiology Society

Subject

Microbiology (medical),General Medicine,Microbiology

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