Author:
Y. Shan Frank,Zhao Dachun,A. Tirado Carlos,Fonkem Ekokobe,Zhang Yi-lu,Feng Dong-xia,H. Huang Jason
Abstract
Glioblastoma (GBM) is a fatal human brain tumor of grade IV/4 by WHO classification, with a very poor prognosis. At the molecular level and clinical, GBM has at least two types, primary and secondary. Each has a different tumorigenesis and clinical presentation. In this chapter, some major molecular biomarkers and diagnostic hallmarks of GBM will be reviewed and discussed.