Author:
Shanmugam Thangapandiyan,Selvaraj Miltonprabu
Abstract
Fluoride (F) is released into the environment through a combination of natural and anthropogenic processes include the weathering from volcanoes, geothermal activity, and marine aerosols. Chronic fluoride exposure has been linked with amyriad of human diseases such as skeletal and dental fluorosis, diabetes, atherosclerosis, cardiovascular diseases, and hyperkeratosis. Since fluoride targets ubiquitous enzyme reactions, it affects nearly all organ systems in animals and humans. Apart from synthetic chemical chelators, studies have been carried out to explore natural antioxidants against F toxicity. Natural products contain substances that inhibit the theoxidation of substrate(s). Antioxidant molecules are thought to play a crucial role in counteracting free-radical-induced damage to macromolecules. In this book chapter literature survey of the different phytoremediation strategy is presented. The results show that natural antioxidants exhibit promising antidote against fluoride-induced toxicity in different mammal systems.
Reference50 articles.
1. Shanthakumari D, Srinivasalu S, Subramanian S. Effects of fluoride intoxication on lipidperoxidation and antioxidant status in experimental rats. Toxicology. 2004;204:219-228
2. Budisa N, Kubyshkin V, Schulze-Makuch D. Fluorine-rich planetary environments as possible habitats for life. Life. 2014;4(3):374-385
3. Nabavi SF, Habtemariam S, Sureda A, Akbar HM, Daglia M, et al. In vivo protective effects of gallic acid isolated from peltiphyllum peltatum against sodium fluoride-induced oxidative stress in rat erythrocytes. Arhiv za Higijenu Rada i Toksikologiju. 2013;64:553-559
4. WHO (World Health Organization). In: Bailey K, Chilton J, et al., editors. Fluoride in Drinking Water. Geneva, Switzerland: WHO Press; 2006
5. Environmental Health Criteria (EHC) 227, Fluorides, World Health Organization, Geneva, Switzerland, 2002
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献