Abstract
This chapter will provide a state of the art of digital health interventions for people with sickle cell disease. It will use WHO classification of digital health interventions to elaborate on existing intervention, the gaps, and how technology could be useful to support people with sickle cell disease. A description of the existing possibilities, the current trends, and the future opportunities will be provided. As well, methodologies to increase patient adherence to digital health interventions, the importance of participatory approaches, open innovation, and patient-led approaches to designing such interventions will be discussed. Importantly, a holistic/planetary health approach will be chosen to introduce the subject and ensure to keep a broad eye on the domain and to include sustainability challenges.