Author:
Aleshire Kayla,Bazzi Rima
Abstract
Current management of perinatal HIV infections and exposures involves the administration of antiretroviral therapy to both the pregnant mother and to her child after delivery. Striving to achieve safe and effective medication management is key in preventing new pediatric HIV infections. Maternal HIV testing and subsequent monitoring can help to identify fetal HIV exposures during pregnancy, maternal nonadherence, insufficient treatment regimens, and otherwise undiscovered exposures during the delivery process. There are several well-constructed guidelines that offer expert references for healthcare providers. This chapter will summarize current recommendations from the United States, with a brief insight into select international guidelines. Although available guidelines provide a structured framework for the healthcare team, there has recently been a significant drive to advance current perinatal management and outcomes.
Reference40 articles.
1. Connor EM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. The New England Journal of Medicine. 1994;331(18):1173-1180. DOI: 10.1056/NEJM199411033311801
2. Fowler MG, Qin M, Fiscus SA, et al. Benefits and risks of antiretroviral therapy for perinatal HIV prevention. The New England Journal of Medicine. 2016;375(18):1726-1737. DOI: 10.1056/NEJMoa1511691
3. Flynn PM, Taha TE, Cababasay M, et al. Prevention of HIV-1 transmission through breastfeeding: Efficacy and safety of maternal antiretroviral therapy versus infant nevirapine prophylaxis for duration of breastfeeding in HIV-1-infected women with high CD4 cell count (IMPAACT PROMISE): A randomized, open-label, clinical trial. Journal of Acquired Immune Deficiency Syndromes. 2018;77(4):383-392. DOI: 10.1097/QAI.0000000000001612
4. Centers for Disease Control and Prevention. HIV Surveillance Report, 2019. Vol. 32 [Internet]. 2021. Available from: http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html. [Accessed: April 18, 2022]
5. World Health Organization. Global Health Sector Strategy on HIV: 2016-2021 Towards Ending AIDS: Prevention of HIV Infection in Infants [Internet] 2016. Available from: https://apps.who.int/iris/bitstream/handle/10665/246178/WHO-HIV-2016.05-eng.pdf. [Accessed: April 18, 2022]
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