Abstract
Brain disorders, particularly those that worsen with age, often classified as neurodegenerative disorders constitute a major problem worldwide owing to their complexity and tremendous challenges with getting befitting therapies for them. Biomaterial technology advancements over the past few years are igniting the hope of increased success in drug discovery and development for neurological and neurodegenerative diseases. In this review, we will discuss an overview of biomaterials used in central nervous system (CNS) disorders and their contextual ideal characteristics, the use of hydrogel and nanogel biomaterials that have been explored for the treatment of various CNS disorders, and how these materials have been utilized. We shall also cover discussions on current trends associated with the use of these materials as well as challenges and prospects in this emerging field.