Genomic Surveillance and Intervention on Dengue Virus in an Urban Setting in the Philippines

Abstract

This is part of the ReMoVE Dengue Program (i.e., research on mosquito, virus, and eco-socioeconomics of dengue) initiated under the auspices of the National Research Council of the Philippines, which started in 2012 aimed to develop locally adapted technologies, products, and systems, which would control the spread of dengue virus and reduce the eco-socioeconomic impact of dengue. Here, will be reported the results of the genomic surveillance of community-collected mosquitoes from a dengue hotspot community of Barangay Old Balara in Quezon City, Philippines using serotype-specific dengue PCR, and the developed antisense RNA product platform for dengue virus control based on surveillance results. Implications and recommendations for this work are outlined.