Abstract
Gallstones in the gallbladder are asymptomatic in many patients but can cause serious morbid and mortal problems in a significant number of patients. In addition to simple symptoms such as nausea, vomiting, and abdominal pain, gallstones can cause serious complications such as cholecystitis, cholangitis, bile duct obstruction, pancreatitis, biliary perforation, biliary fistula, and biliary neoplasty. It is important that the problems that may arise due to gallstones are adequately known by physicians and even by patients and their relatives. Being unaware of the possible effects of gallstones can lead to under-treatment and serious complications. Assigning a score to the symptoms and clinical conditions associated with gallstones in proportion to their severity and making accurate comparisons with these scores in clinical trials is important for the use of common language and convenience in studies.
Reference67 articles.
1. Wesdorp I, Bosman D, de Graaff A, Aronson D, van der Blij F, Taminiau J. Clinical presentations and predisposing factors of cholelithiasis and sludge in children. Journal of Pediatric Gastroenterology and Nutrition. 2000;31(4):411-417. DOI: 10.1097/00005176-200010000-00015
2. Palasciano G, Portincasa P, Vinciguerra V, et al. Gallstone prevalence and gallbladder volume in children and adolescents: An epidemiological ultrasonographic survey and relationship to body mass index. The American Journal of Gastroenterology. 1989;84(11):1378-1382
3. Ana Cristina AT, Leal AJG, Velhote MCP, Gonlçalves MEP, Tannuri U. Management of gallstone disease in children: A new protocol based on the experience of a single center. Journal of Pediatric Surgery. 2012;47(11):2033-2038. DOI: 10.1016/j.jpedsurg.2012.06.010
4. Gökçe S, Yıldırım M, Erdoğan D. A retrospective review of children with gallstone: Single-center experience from Central Anatolia. The Turkish Journal of Gastroenterology. 2014;25(1):46-53. DOI: 10.5152/tjg.2014.3907
5. Roslyn JJ, Berquist WE, Pitt HA, et al. Increased risk of gallstones in children receiving total parenteral nutrition. Pediatrics. 1983;71(5):784-789