Author:
Islam Aqib Amjad,Ijaz Muhammad,Shoaib Muhammad,Muzammil Iqra,Iftikhar Hussain Hafiz,Zaheer Tean,Ahmed Rais,Sarwar Iqra,Razzaq Khan Yasir,Aamir Naseer Muhammad
Abstract
Staphylococcus aureus is a major causative agent of intra-mammary infections in dairy animals with potential virulence of surface components, toxins, and extracellular enzymes. About 74% quarter prevalence of S. aureus in bovine udder with overall prevalence exceeding 61% in dairy animals. About 17 different serotypes of dairy originated S. aureus have been reported with 24 virulence coding genes for leukocidins (lukED/lukM), pyrogenic toxin super antigen (PTSAg), haemolysins (hla-hlg), toxic-shock syndrome toxin (tst), enterotoxins (sea-seo, seu), exfoliative toxins (eta, etb), and genes for methicillin (mecA) and penicillin (blaZ) resistance. Attainment of refuge inside the macrophages and neutrophils is a major cause of S. aureus mastitis persistence. Mammary prebiotics and probiotics are recently being used as alternatives to antibiotic for the prevention of mastitis. Literature showed anti- staphylococcus vaccines with different results depending upon types of immunization, route of administration and adjuvant used. Studies has shown that herd specific as well as commercial S. aureus vaccines reduce new infections in dairy animals. Experiments are still in progress for the use of vaccines against S. aureus mastitis with optimal efficacy and reliability. Perhaps, there might be bright future because of highly satisfactory trial results of mastitis vaccines in the lab animals.
Reference89 articles.
1. Shoaib M, Rahman SU, Aqib AI, Ashfaq K, Naveed A, Kulyar MF-A, et al. Diversified Epidemiological Pattern and Antibiogram of mecA Gene in Staphylococcus aureus Isolates of Pets, Pet Owners and Environment. Pak Vet J. 2020;40(3):331-336
2. Aqib A, Nighat S, Ahmed R, Sana S, Jamal M, Kulyar MF, et al. Drug Susceptibility Profile of Staphylococcus aureus Isolated from Mastitic Milk of Goats and Risk Factors Associated with Goat Mastitis in Pakistan. Vol. 51. Pakistan J. Zool., Vol. 51, Iss. 1, pp. 307-315 Read more at http://researcherslinks.com/current-issues/Drug-Susceptibility-Profile-of-Staphylococcus/20/1/1880/html#KolwAq8XDDQ2YXZo.99; 2018. 307-315 p
3. A Begum H, S Uddin M, J Islam M, Nazir KHMNH, Islam M, Rahman MT. Detection of biofilm producing coagulase positive Staphylococcus aureus from bovine mastitis, their pigment production, hemolytic activity and antibiotic sensitivity pattern. 4(1 & 2): J. Bangladesh Soc. Agric. Sci. Technol.4(1 & 2): 97-100; 2007
4. Naseer MA, Aqib AI, Ashar A, Saleem MI, Shoaib M, Kulyar MF-A, et al. Detection of Altered Pattern of Antibiogram and Biofilm Character in Staphylococcus aureus Isolated From Dairy Milk. Pakistan J Zool. 2020;
5. Basanisi MG, La Bella G, Nobili G, Franconieri I, La Salandra G. Genotyping of methicillin-resistant Staphylococcus aureus (MRSA) isolated from milk and dairy products in South Italy. Food Microbiol. 2017;62:141-146
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献