Abstract
Over the past decade, numerous research studies have shown that the immune system’s capacity for creating antibodies after getting vaccinated is better in those who exercise are physically active. Authoritative studies show that exercise is an important ally of the vaccine, amplifying its effectiveness. The immune response to vaccines is usually lower in the elderly population. Several strategies have been used to help overcome this problem. Recently, studies in humans and animals have shown that exercise increases antigen-specific blood antibody levels following vaccination. Exercise has been considered as an effective way to improve vaccine response in the elderly population. In this chapter, we will discuss the effect of exercise on vaccine response. This study summarizes the current understanding of exercise and antibody production. In order to develop intervention strategies, it will be necessary to further elucidate the predisposing factors and mechanisms behind exercise induce antibody response.
Reference62 articles.
1. Havers F, Sokolow L, Shay DK, Farley MM, Monroe M, Meek J, et al. Case-control study of vaccine effectiveness in preventing laboratory-confirmed influenza hospitalizations in older adults, United States, 2010-2011. Clinical Infectious Diseases. 2016;63(10):1304-1311
2. Campbell JP, Turner JE. Debunking the myth of exercise-induced immune suppression: Redefining the impact of exercise on immunological health across the lifespan. Frontiers in Immunology. 2018;9:648
3. Khammassi M, Ouerghi N, Said M, Feki M, Khammassi Y, Pereira B, et al. Continuous moderate-intensity but not high-intensity interval training improves immune function biomarkers in healthy young men. Journal of Strength and Conditioning Research. 2020;34(1):249-256
4. WHO. Summary report on first, second and third generation smallpox vaccines. WHO Report. 2013. p. 33
5. Stratton K, Ford A, Rusch E, Clayton EW. Adverse Effects of Vaccines: Evidence and Causality. Washington DC: The National Academies Press; 2012. pp. 1-894