Basic mechanisms of multisystemic inflammatory syndrome and severe acute respiratory syndrome coronavirus 2

Abstract

Multisystemic inflammatory syndrome is a condition developed by various factors such as chronic diseases, diverse body traumas, postoperative complications, and hypoxia. Within the main characteristics of this pathological condition, there is an increase in body temperature, free radicals, proinflammatory cytokines, lymphocytes, and even apoptosis. However, gravity depends on each of the organisms, its characteristics, as well as from the presence of other conditions such as overweight, obesity, and in recent years the infection has al severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), etc. With the above, it is essential to mention that the body uses several cell and molecular mechanisms to counteract the effects of inflammation for a long time. Therefore, life expectancy will depend on each patient’s genetic, metabolic, and physiological response characteristics. This chapter describes the basic mechanisms given during the development of multisystemic inflammatory syndrome.