Aspergillus and Aspergillosis in People with Chronic Diseases

Abstract

Numerous human diseases are caused by Aspergillus species. Mold infections can be more severe in people with weakened immune systems and chronic illnesses. People with underlying chronic conditions are more likely to contract an Aspergillus infection than immunocompromised patients, who are more likely to develop an invasive infection with these opportunistic molds. These disorders include Aspergillus bronchitis, allergic bronchopulmonary aspergillosis, diabetes, cystic fibrosis, severe asthma with fungal sensitivity, and other inflammatory and allergic conditions. The impact of Aspergillus infections in patients with selected chronic infections and the treatment of these infections are discussed in this review along with the most recent research on these topics.