Exploring the Therapeutic Potential from Moringa oleifera and Urtica dioica Bioactive Compounds in Managing Diabetes and Insulin Resistance

Abstract

Diabetes is one of the ubiquitous metabolic disorders, indicating increasing chronic blood levels (chronic hyperglycaemia). Its three types are mostly caused by different pathogenic conditions (disorders in the secretion and/or regulation blood sugar insulin levels), often resulting from defects in insulin secretion and abnormal glucose tolerance. In addition, most people with diabetes have type 2 diabetes, which is characterised by insulin resistance and progressive beta-cell failure. Recently, there has been a growing demand for medicinal plants traditionally used to manage diabetes and its complications, as the insulin use is somewhat correlated with side effects. The current chapter focused on two medicinal plants, Moringa oleifera and Urtica dioica. The chosen plants have shown therapeutic potential as natural diabetes remedies owing to their bioactive compounds. The chosen plants have shown potential as natural diabetes remedies owing to their diverse bioactive compounds range and their effect on insulin resistance and glucose levels. Additionally, they exhibit hypoglycaemic features making them promising candidates for further diabetes management investigation. Besides, because of their bioactive phytochemicals, they do have the ability to prevent the diabetes’s onset. Of note, this chapter aims to explore their effects on blood sugar regulation with a focus on managing diabetes potential.