Author:
Mollik Murshida,Islam Hamidul
Abstract
Recent studies have claimed that people are now greatly relying on synthetic drug without considering any side effect; however, all the synthetic drugs have been formulated commercially by following the invention of an authentic source of crude drug; hence, people are still directly or indirectly dependent on natural source of medicine. Recently, I have completed a research work on black pepper (Piper nigrum), and piperine (in a crystal form) was isolated as a mother bioactive compound from black pepper through a plenty of in vitro investigations. After that, I have experimented some in vitro analysis to evaluate the antioxidant power of that pure compound, and it was found that the crystal compound has strong antioxidant power. After doing some theoretical analysis, it has been identified that piperine may exist in other medicinal plants also, and many plants belonging to the same species can able to show multiple types of biological activities, which actually reflected the diversity of bioactive compounds in nature. People can benefit from different types of bioactive compounds, such as piperine, if we biosysthesize and use them commercially.
Reference54 articles.
1. Gu J, Gui Y, Chen L, Yuan G, Lu HZ, Xu X. Use of natural products as chemical library for drug discovery and network pharmacology. PLoS One. 2013;8:e62839
2. Shinde VM, Dhalwal K, Potdar M, Mahadik KR. Application of quality control principles to herbal drugs. International Journal of Phytomedicine. 2009:1(1):4-8
3. Sumner J. The Natural History of Medicinal Plants. London: Timber Press; 2000. p. 16
4. Yarnell ND, Abascal JD. Dilemmas of traditional botanical research. Herbal Gram. 2002;55:46-54
5. Fabricant DS, Farnsworth NR. The value of plants used in traditional medicine for drug discovery. Environmental Health Perspectives. 2001;109(Suppl 1):69-75