Gastroesophageal Reflux Disease and Obesity

Abstract

The global rise of gastroesophageal reflux disease (GERD) prevalence makes it one of the most common diagnoses performed in a daily practice. Obesity significantly contribute to GERD development, accordingly, it has accounted for the increasing cases of GERD. Obesity can disrupt the esophagogastric junction integrity, which promote the development of GERD and its complication. The frequency of GERD symptoms and its mucosal complications also found more often in obesity. The parallel increase of both condition has initiated numerous studies to determine the most beneficial therapeutic options in managing this challenging condition. Current available therapy for GERD in obesity including weight reduction, pharmacotherapy, and surgery.