Abstract
Parkinson’s disease (PD) is a vast and complex syndrome. Far more than a mere disorder of motor function, it encompasses autonomic, cognitive, emotional and systemic symptoms. Moreover, pain has increasingly been recognized as an associated feature. Within pain and headache, migraine can bear a unique relation with PD. We hereby review the scientific literature on the relation between PD, pain and migraine and analyze the pathophysiological underpinnings and suggest adjustments in the management to tentatively improve clinical outcomes in this setting.
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