Iron Oxide Nanoparticles and Nano-Composites: An Efficient Tool for Cancer Theranostics

Abstract

In recent years, functional Iron oxides nanoparticles and nano-composites have gained a special traction in the field of nano-biomedicine, owing to their multifunctional capabilities that includes the inherent magnetic resonance imaging, magnetic bioseparation, cargo delivery and magnetic hyperthermia behavior. Interestingly, there are various forms of iron oxides available, with each form having their own specific characteristics. The different polymorphic forms of iron oxides are obtained through various synthetic routes and are usually surface modified to prevent their oxidation. The chapter shall encompass the synthesis and surface modification of Iron oxides nanoparticles, physicochemical properties, and theranostic application of the magnetic iron oxide nanoparticles in cancer. Also, the future directions of Iron oxide nanoparticles and nano-composites towards the achievement of clinically realizable nanoformulation for cancer theranostic applications were highlighted.