Author:
Santillán Roldan Pablo,Cepeda Mora Andrés,Armas Cruz Pablo,Sarmiento Benavides Andres,Victoria Iturralde Arcos María,Carlos Jacome Sayay Juan,Aucapiña Chocho Elisa,Isabel Jara Jimbo María
Abstract
Worldwide, every minute a woman dies due to complications during pregnancy, obstetric hemorrhage being the leading cause. However, most of these deaths are preventable with prompt recognition and management. The main objective of its management in the initial phase of resuscitation is to aggressively optimize macro and microhemodynamic parameters by ensuring effective resuscitation. Patient blood management (PBM) consists in the timely application of evidence-based medical and surgical procedures aimed at maintaining hemoglobin concentration, optimizing hemostasis and minimizing blood loss to improve patient outcome, all of these based in three pillars: endogenous erythropoiesis, platelet and coagulation factors function and physiological reserve of anemia. PBM consider various strategies to reach the main goal, including transfusional, non-transfusional and surgical measures. At preoperative period the prevention and treatment of anemia is the corner stone of the PBM guideline. Once at the operating room the fluid management, uterotonic and pro-coagulant drugs, fibrinogen and blood products transfusion play a key role and surgical techniques have to be done if the patient life is threatened. Manage postpartum anemia by appropriate iron administration. Optimize the patient’s physiological response to anemia, treat infections and maximize oxygen delivery to minimize transfusions if they are not strictly necessary.
Reference40 articles.
1. Main EK, McCain CL, Morton CH, Holtby S, Lawton ES. Pregnancy-related mortality in California: causes, characteristics, and improvement opportunities. Obstetrics and Gynecology. 2015;125(4):938-947. Available from: https://pubmed.ncbi.nlm.nih.gov/25751214/
2. Shields LE, Wiesner S, Klein C, Pelletreau B, Hedriana HL. Use of maternal early warning trigger tool reduces maternal morbidity. American Journal of Obstetrics and Gynecology. 2016;214(4):527.e1-527.e6. Available from: https://pubmed.ncbi.nlm.nih.gov/26924745/
3. Anderson JM, Etches D. Prevention and management of postpartum haemorrhage. BJOG. 2022;124(5):e106-e1049. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.14178
4. WHO recommendations for the prevention and treatment of postpartum haemorrhage. [cited 2022 Dec 5]; Available from: www.who.int/maternal_child_adolescent
5. Chestnut D et al. Chestnut’s Obstetric Anesthesia Principles and Practice. Sixth ed. Elsevier Health; 2019. p. 1324