Author:
Nováková Noemi,Nezval Martin,Molnárová Viktória
Abstract
The effects of pathophysiology-oriented treatment using metformin and/or insulin analogs and/or incretin GLP-1 receptor agonists and/or dapagliflozin and/or pioglitazone were individually evaluated in ten people with type 2 diabetes (T2D) at an urban diabetes center. Some of them had microangiopathy and/or neuropathy and/or nephropathy. The observation period ranged from 2 to 12 years. Treatment efficiency was estimated according to changes in HbA1c, body mass, insulin dose per day, blood pressure, lipoproteins, albuminuria, estimated glomerular filtration rate (eGFR), and general clinical condition. The results suggest that adequate education, early implementation of self-monitoring of capillary plasma glucose (SMPG)/continuous glucose monitoring (CGM), and long-term carefully selected/combined medication (see above) appears to result in improved metabolic control and enhanced quality of life for people with T2D.