Abstract
Insulin is an essential protein hormone secreted by the beta cells of the islet of Langerhans in the pancreas which is involved in glucose homeostasis, cell metabolism and mitogenesis. It is essential that healthcare providers are conversant with the normal physiology of this protein in the human body, to aid them in clinical decision-making when processes pertaining to this crucial substance go aberrant in the “corpus”. Healthcare providers will then be able to better appreciate the pathophysiology of disease states pertaining to this hormone most importantly diabetes which is a great cause of global morbidity and mortality. Healthcare providers should be comfortable especially in recognizing these disease states clinically and instituting the most appropriate form of management in-line with the most recent evidence-based medicine to improve patient outcomes.