Author:
Sanyaolu Adekunle,Okorie Chuku,Marinkovic Aleksandra,Hamdy Kareem,Prakash Stephanie,Patidar Risha,Fahad Abbasi Abu,Desai Priyank,Jan Abdul,Mangat Jasmine
Abstract
In the early twenty-first century, measles was completely eradicated in the United States of America (USA) and almost eliminated in Canada. This was greatly due to most of the population being vaccinated against the virus. In 2018 and 2019, the USA and Canada experienced a rapidly developing measles virus outbreak due to growing debates about vaccine efficacy and side effects. Therefore, some people refused to vaccinate their children against measles, as well as many other life-threatening preventable diseases. This led to a major measles outbreak and health concern in the USA, Canada, and globally. Some countries including the Democratic Republic of the Congo (DRC) reported a significant number of cases and casualties resulting from measles, mainly due to the lack of funding for vaccines, as well as inadequate vaccination coverage in certain socio-demographic areas. People traveling from these countries can easily transmit the disease, though there has been a steep decline in cases since the travel ban due to coronavirus disease-2019 (COVID-19). The number of unvaccinated children currently in the USA and Canada has quadrupled since 2001. Over the past couple of years, most of the measles cases have been diagnosed in those who either did not receive the measles vaccine or complete the recommended doses of the vaccine. This paper reviews the measles outbreak, in recent years, among unvaccinated individuals in the USA, Canada, and globally.
Reference33 articles.
1. CDC Measles (Rubeola): Genetic analysis of measles viruses. Centers for Disease Control and Prevention. June 5, 2018. [Accessed September 13, 2020 https://www.cdc.gov/measles/lab-tools/genetic-analysis.html]
2. Obam Mekanda FM, Monamele CG, Nemg FBS, Yonga GM, Ouapi D, et al. Molecular characterization of measles virus strains circulating in Cameroon during the 2013-2016 epidemics. PLoS One. 2019; 14(9): e0222428. [Accessed September 13, 2020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760898]
3. Jiang Y, Qin Y, Chen M. Host-pathogen interactions in measles virus replication and anti-viral immunity. Viruses. November 2016; 8(11): 308. [Accessed September 13, 2020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127022]
4. CDC. Measles: Epidemiology and prevention of vaccine-preventable diseases. Centers for Disease Control and Prevention. April 2015; 13: 209-230. [Accessed September 13, 2020 https://www.cdc.gov/VACCINES/PUBS/pinkbook/downloads/meas.pdf]
5. Kondamudi NP, Waymack JR. Measles. StatPearls. 10 August 2020. [Accessed September 13, 2020 https://www.ncbi.nlm.nih.gov/books/NBK448068]