The Effect of Administration of Substance Abuse among People Suffering from Substance Use Disorder on the Digestive System: A Systematic Review

Abstract

The administration of adulterated illicit drugs is a serious public health concern worldwide. The highly affected participants are the youth who develop substance use disorder over time. The serious concern is the rate at which people suffering from substance use disorder (SUD) develop a lack of appetite. The study aimed to compile a manuscript to address the effect of the administration of illicit drugs on metabolism patterns. Several search engines were used to gather the data from several authors. There is clear evidence that the administration of adulterated drugs might affect their digestive metabolism pattern. Other studies have observed that the administration of cannabis might improve the appetite of those who suffer from SUD. Therefore, the health professionals who aid people suffering from SUD need to first introduce the eating pattern during the mitigation strategies. There is also clear evidence that highly affects the digestive component of the liver. The biotransformation of heroin and its metabolites involves hydrolytic reactions, that occur in the liver. Therefore, decreased food intake and hormone dysregulation modify the mechanisms of satiety. Further investigation is needed to assess the pharmacokinetics of adulterated drugs with other components of the digestive system.