Chronic Venous Ulcer

Abstract

This research review is endeavoring to shed the light on the cause and effect of Chronic Venous Ulcer (CVU) in line with its therapeutic procedures. In the last two decades, a lot of the changes occurred in strategy of wound management through developing adjunctive therapy that supported wound healing. Eventually, the latest development was in platelet concentration technology produced the platelet-rich fibrin (PRF). It was categorized as the 2nd generation of platelet concentration family after Platelet Rich Plasma (PRP). Considering that Venous Leg Ulcers (VLUs) accounted for 70% of all leg ulcers and estimated one percent of the population where age as an essential factor has increased its prevalence. The chronicity and refractory nature of venous ulcer had a great effect on the quality of life and work productivity of patients apart from, the expenditure of significant amount of medical resources and efforts. Therefore, the ultimate goal of (VLU) management was to induce a rapid healing without recurrence which mainly helped to improve the quality of life (QoL). The first therapeutic procedure used in treatment of VLU was compression therapy where the application of effective graduated compression decreased the overload in venous system and venous reflux. Furthermore, it accelerated the capillary of blood flow and decreased the capillary of fluid leakage which in return alleviated the limb edema.