1. Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes. Official Journal of the European Union L 276/33. Available from: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2010:276:0033:0079:en:PDF
2. EU (2013) Royal Decree 53/2013, of 1 February, which establishes the basic rules applicable for the protection of animals used in experimentation and other scientific purposes, including teaching. BOE 34 8/2/2013: 11370-11421 (Consulta: 20/09/2014). Available in: https://www.boe.es/boe/dias/2013/02/08/pdfs/BOE-A-2013-1337
3. Russell WMS, Burch RL. The Principles of Humane Experimental Technique. Methuen, Londres. Potters Bar, England: Special Edition, Universities Federation for Animal Welfare; 1959
4. Festing MF, Altman DG científicos. DOCE L276 20/10/2010: 33-79. Guidelines for the design and statistical analysis of experiments using laboratory animals. Institute for Laboratory Animal Research Journal. 2002;43(4):244-258. Erratum in: Institute for Laboratory Animal Research Journal. 2005;46(3):320
5. Dell RB, Holleran S, Ramakrishnan R. Sample size determination. Institute for Laboratory Animal Research Journal. 2002;43(4):207-213. Erratum in: Institute for Laboratory Animal Research Journal. 2003;44(3):239. PMCID: PMC3275906 NIHMSID: NIHMS351497